5d80d7912b 1998; Vanderpump et al. Gradual tapering of the dose of prednisolone and continuation of CBZ (or MMI) may then be necessary. Overall the average half life of amiodarone is 40 days with that of DEA, its principle metabolite, being 57 days. (2010) Amiodarone: Review of pulmonary effects and toxicity. FootnotesThis article received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. 1988; Braverman et al. 1986] following its discovery in 1961 at the Labaz company in Belgium [Deltour et al.
1993]. (1993) Thyrotoxicosis followed by hypothyroidism in patients treated with amiodarone. It was originally introduced as an antianginal compound in 1962 [Rao et al. 2002; Trip et al. (1986) Amiodarone, thyroid hormone indexes, and altered thyroid function: Long-term serial effects in patients with cardiac arrhythmias. ConclusionsAmiodarone continues to be a very useful and extensively utilized antiarrhythmic drug. None declared. In the event of thyroid dysfunction on amiodarone, the decision of whether to continue or stop amiodarone remains complex, particularly in cases of AIT. (2002) Iopanoic acid rapidly controls type I amiodarone-induced thyrotoxicosis prior to thyroidectomy.
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